as Giovanni Auditore

as Rodrigo Borgia

as Federico Auditore

as Ezio Auditore da Firenze

as Lorenzo Medici

as Uberto Alberti

as Pope Sixtus IV

as Galeazzo Maria Sforza

as Silvio Barbarigo

as Marco Barbarigo

as Monk Maffei

as Maria Auditore

as Claudia Auditore

as Lampugnari

as Monk/Servant

as Ezio's Girlfriend