with 22 episodes premiered on September 11, 2000

Confronted with failing marriages, new jobs and therapy, four whip-smart professional women turn to one another as they struggle with life's challenges.

with 22 episodes premiered on September 10, 2001

After a disastrous vacation in Jamaica, the second season finds Joan and Toni making amends and vowing to never let a man come between them again.

with 25 episodes premiered on September 23, 2002

Exes and woes test close friends Joan, Toni, Maya and Lynn as they deal with marital, financial and emotional drama.

with 24 episodes premiered on September 15, 2003

This season, Toni adjusts to married life, Maya pursues her passion, Lynn searches for answers, and Joan tries to figure out her future.

with 22 episodes premiered on September 20, 2004

Still tight as ever, Joan, Toni, Maya and Lynn start new chapters in their lives involving career moves, motherhood and complicated relationships.

with 22 episodes premiered on September 19, 2005

The girls return for a new round of relationship trials and triumphs, including another walk down the aisle and tumultuous affairs.

with 22 episodes premiered on October 2, 2006

Joan tries to make amends with the girls and Lynn pursues her music career. Is the special bond between these women dissolving?

with 13 episodes premiered on October 1, 2007

New hurdles, same friends. In the final season, Joan, Maya, Lynn and William face tough decisions in their careers, love and parenthood.