Season 4 poster

Season 4

(2007)

Overview

Enter a world of change in the irresistible and unforgettable fourth season of Grey's Anatomy. Love, lies, and family ties are revealed as the surgeons of Seattle Grace discover that their choices have major unintended consequences. And coupled with the arrival of some very eager new interns, life at the hospital sizzles with more emotion, excitement, and heartbreak than ever before.

Cast

Ellen Pompeo as Meredith Grey
Ellen Pompeo

as Meredith Grey

Chandra Wilson as Miranda Bailey
Chandra Wilson

as Miranda Bailey

Sandra Oh as Cristina Yang
Sandra Oh

as Cristina Yang

James Pickens Jr. as Richard Webber
James Pickens Jr.

as Richard Webber

Katherine Heigl as Izzie Stevens
Katherine Heigl

as Izzie Stevens

Justin Chambers as Alex Karev
Justin Chambers

as Alex Karev

T.R. Knight as George O'Malley
T.R. Knight

as George O'Malley

Sara Ramirez as Callie Torres
Sara Ramirez

as Callie Torres

Patrick Dempsey as Derek Shepherd
Patrick Dempsey

as Derek Shepherd

Eric Dane as Mark Sloan
Eric Dane

as Mark Sloan

Chyler Leigh as Lexie Grey
Chyler Leigh

as Lexie Grey

Episodes

A Change Is Gonna Come poster

A Change Is Gonna Come 7.6

September 27, 2007

Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of …

Love/Addiction poster

Love/Addiction 7.4

October 4, 2007

A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in …

Let the Truth Sting poster

Let the Truth Sting 7.6

October 11, 2007

The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior susp…

The Heart of the Matter poster

The Heart of the Matter 7.5

October 18, 2007

A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer…

Haunt You Every Day poster

Haunt You Every Day 7.6

October 25, 2007

It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based …

Kung Fu Fighting poster

Kung Fu Fighting 6.8

November 1, 2007

A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are compet…

Physical Attraction, Chemical Reaction poster

Physical Attraction, Chemical Reaction 7.4

November 8, 2007

Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken a…

Forever Young poster

Forever Young 7.3

November 15, 2007

There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when…

Crash Into Me (1) poster

Crash Into Me (1) 7.8

November 22, 2007

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them,…

Crash Into Me (2) poster

Crash Into Me (2) 7.7

December 6, 2007

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; D…

Lay Your Hands on Me poster

Lay Your Hands on Me 6.7

January 10, 2008

George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith …

Where The Wild Things Are poster

Where The Wild Things Are 7.4

April 24, 2008

Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose…

Piece of My Heart poster

Piece of My Heart 7.4

May 1, 2008

Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredi…

The Becoming poster

The Becoming 6.7

May 8, 2008

The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to …

Losing My Mind poster

Losing My Mind 6.8

May 15, 2008

Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica t…

Freedom (1) poster

Freedom (1) 7.2

May 22, 2008

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex…

Freedom (2) poster

Freedom (2) 8.0

May 22, 2008

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex…