Season 5 poster

Season 5

(2008)

Overview

Live for the moment. Dive deeper into the lives and loves of "Grey's Anatomy"! The doctors struggle and thrive as they enter uncharted territories of life. Discover what happens in the on-again, off-again world of Derek and Meredith, and witness the budding relationship between Cristina and Owen, Seattle Grace's newest doctor.

Cast

Ellen Pompeo as Meredith Grey
Ellen Pompeo

as Meredith Grey

Chandra Wilson as Miranda Bailey
Chandra Wilson

as Miranda Bailey

Sandra Oh as Cristina Yang
Sandra Oh

as Cristina Yang

James Pickens Jr. as Richard Webber
James Pickens Jr.

as Richard Webber

Kevin McKidd as Owen Hunt
Kevin McKidd

as Owen Hunt

Katherine Heigl as Izzie Stevens
Katherine Heigl

as Izzie Stevens

Justin Chambers as Alex Karev
Justin Chambers

as Alex Karev

T.R. Knight as George O'Malley
T.R. Knight

as George O'Malley

Sara Ramirez as Callie Torres
Sara Ramirez

as Callie Torres

Patrick Dempsey as Derek Shepherd
Patrick Dempsey

as Derek Shepherd

Eric Dane as Mark Sloan
Eric Dane

as Mark Sloan

Chyler Leigh as Lexie Grey
Chyler Leigh

as Lexie Grey

Episodes

Dream a Little Dream of Me (1) poster

Dream a Little Dream of Me (1) 7.6

September 25, 2008

As Meredith and Derek begin to find that their "happily ever after" is anything but easy, Cristina develops a crush on …

Dream a Little Dream of Me (2) poster

Dream a Little Dream of Me (2) 7.7

September 25, 2008

Alex is offended when Izzie talks about how great a man Alex is to Meredith. Derek is stabbed with the scalpel in the p…

Here Comes the Flood poster

Here Comes the Flood 7.6

October 9, 2008

When the plumbing springs a leak, chaos breaks out at Seattle Grace as the Chief tries to put in place new teaching met…

Brave New World poster

Brave New World 7.6

October 16, 2008

Meredith is sent into a state of panic when Derek finds her mother's diary in the house. Meanwhile, Callie stresses whi…

There's No 'I' in Team poster

There's No 'I' in Team 7.6

October 23, 2008

Bailey heads up a "domino procedure" in which each surgery hinges on the one preceding it. Meanwhile, Derek gets sole c…

Life During Wartime poster

Life During Wartime 7.7

October 30, 2008

The chief gives Bailey new power and responsibility. He also gives her a very difficult surgical assignment: remove a g…

Rise Up poster

Rise Up 6.8

November 6, 2008

When the Chief makes an announcement that a solo surgery is up as an award, the residents are sent into a frenzy all tr…

These Ties That Bind poster

These Ties That Bind 7.3

November 13, 2008

One of Meredith's oldest friends, Sadie, becomes an intern at Seattle Grace, but Mer's friends are less-than-welcoming …

In the Midnight Hour poster

In the Midnight Hour 7.8

November 20, 2008

Meredith, Cristina and Bailey come to Lexie and Sadie's rescue when a routine surgery goes horribly wrong, as Owen and …

All by Myself poster

All by Myself 7.8

December 4, 2008

Cristina is awarded the first solo surgery among the residents, but she is forced to give it up and choose her replacem…

Wish You Were Here poster

Wish You Were Here 7.5

January 8, 2009

Bailey teams with Seattle Grace's new pediatric surgeon, Dr. Arizona Robbins, to save the life of a young patient near …

Sympathy for the Devil poster

Sympathy for the Devil 7.2

January 15, 2009

Derek's mother, Carolyn, makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conc…

Stairway to Heaven poster

Stairway to Heaven 8.5

January 22, 2009

Bailey grows desperate as a patient's condition becomes more and more dire. Everyone in the hospital is stepping up to …

Beat Your Heart Out poster

Beat Your Heart Out 7.7

February 5, 2009

Now that Derek has the engagement ring, he searches for the perfect way to propose to Meredith, as Lexie demands that M…

Before and After poster

Before and After 7.6

February 12, 2009

Addison, Naomi and Sam rush the ailing Archer to Seattle Grace and reunite with old friends Derek and Mark to help save…

An Honest Mistake poster

An Honest Mistake 7.8

February 19, 2009

Derek's confidence is shaken like never before as he faces off with Addison over what course is best for their dying pr…

I Will Follow You Into the Dark poster

I Will Follow You Into the Dark 7.8

March 12, 2009

Derek decides to quit after learning that more of his patients have died than survived; Izzie's interns make an unsettl…

Stand By Me poster

Stand By Me 8.3

March 19, 2009

After his fellow surgeons try and fail to bring Derek back to work, Meredith must summon the strength to convince him. …

Elevator Love Letter poster

Elevator Love Letter 8.3

March 26, 2009

All eyes are on Derek as he is set to perform his first surgery after his breakdown; attention is also set on Izzie, wh…

Sweet Surrender poster

Sweet Surrender 7.7

April 23, 2009

As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith's wedding.

No Good at Saying Sorry (One More Chance) poster

No Good at Saying Sorry (One More Chance) 7.7

April 30, 2009

As preparations continue for Meredith and Derek's wedding, Izzie receives a surprise hospital visit from her handful-of…

What a Difference a Day Makes poster

What a Difference a Day Makes 8.3

May 7, 2009

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car …

Here's to Future Days poster

Here's to Future Days 8.0

May 14, 2009

In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whethe…

Now or Never poster

Now or Never 8.6

May 14, 2009

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughou…